Understanding Compounded Medications

NAD+ nasal spray is a compounded formulation prescribed under federal law but not FDA-approved, meaning it has not undergone FDA review for safety, efficacy, or manufacturing quality. Your Good Medics provider may recommend NAD+ nasal therapy based on your individual needs, symptoms, and health goals.

Warning: Risks Associated with NAD+ Therapy

Although NAD+ (nicotinamide adenine dinucleotide) is a naturally occurring coenzyme in the body, high-dose or compounded formulations may carry risks, particularly in individuals with underlying health conditions or sensitivities.

Potential risks include:

• Nasal irritation or congestion

• Headache or lightheadedness

• Nausea or gastrointestinal discomfort

• Allergic reaction to any component of the compound

• Heart palpitations or increased anxiety in sensitive individuals

It is important to discuss all potential risks and benefits with your provider before beginning NAD+ therapy.

What is NAD+ Used For?

NAD+ therapy is often used to support cellular energy production, mitochondrial health, and cognitive function. It may be recommended in the context of:

• Chronic fatigue or low energy

• Brain fog or cognitive decline

• Mood disturbances

• Sleep disruption

• Detoxification protocols

• Anti-aging and longevity support

• Recovery from illness or burnout

NAD+ levels naturally decline with age, and replenishing them may support overall metabolic and neurological function.

Limitations of Use

NAD+ nasal spray is not intended for use as a cure or substitute for standard medical care. It is not approved to treat any specific disease and should not be used as a replacement for medications prescribed for chronic conditions unless advised by a healthcare professional.

Do not use NAD+ nasal spray to self-treat serious illnesses without medical supervision.

Who Should Not Use NAD+ Nasal Spray?

Do not use NAD+ nasal spray if you:

• Are allergic to NAD+ or any ingredient in the spray

• Have active nasal or sinus infections

• Have had recent nasal surgery or trauma

• Are pregnant or breastfeeding (safety not established)

• Experience uncontrolled high blood pressure or severe anxiety

Consult your provider if you have any chronic conditions before beginning treatment.

How to Take NAD+ Nasal Spray

NAD+ is administered as a nasal spray, typically once or twice daily. Your provider will guide you on dosage and frequency based on your health goals.

General instructions:

1. Blow your nose gently before use.

2. Shake the bottle if instructed.

3. Insert the nozzle into one nostril, spray, and inhale gently through the nose.

4. Repeat in the other nostril if directed.

5. Avoid blowing your nose for 10–15 minutes after administration.

What to Discuss with Your Provider

Before starting NAD+ nasal spray, inform your provider if you:

• Take stimulant medications or supplements

• Have heart conditions or anxiety disorders

• Are undergoing other detox or anti-aging therapies

• Are using nasal corticosteroids or other intranasal medications

Serious Side Effects

Seek immediate medical attention if you experience:

• Difficulty breathing

• Facial or throat swelling

• Rapid or irregular heartbeat

• Severe dizziness or loss of consciousness

Common Side Effects

Side effects are typically mild but should be monitored:

• Temporary nasal burning or irritation

• Sneezing or watery eyes

• Headache

• Mild nausea or upset stomach

• Insomnia or restlessness (especially if used late in the day)

Monitoring During NAD+ Therapy

While formal lab monitoring may not be required, follow-up visits are encouraged to assess how you are responding to treatment and adjust dosing as needed.

Your provider may recommend:

• Energy level and cognitive function check-ins

• Sleep and mood assessments

• Review of any new or worsening symptoms

Reporting Side Effects

If you experience concerning side effects, contact your Good Medics provider. You may also report them to the FDA MedWatch program at 1-800-FDA-1088 or visit www.fda.gov/medwatch.