Understanding Compounded Medications

Sermorelin is a compounded peptide therapy prescribed under federal law but is not FDA-approved, which means it does not undergo FDA review for safety, effectiveness, or manufacturing quality. Your Good Medics provider may prescribe Sermorelin based on your specific symptoms, health status, and treatment goals.

Warning: Risks Associated with Sermorelin Therapy

Sermorelin is a synthetic peptide analog of growth hormone-releasing hormone (GHRH). It stimulates your pituitary gland to naturally increase growth hormone (GH) production. While generally considered safe, it may carry risks and side effects—especially when used without medical supervision or in individuals with certain medical conditions.

Potential risks include:

• Injection site reactions (pain, swelling, redness)

• Water retention or swelling in the extremities

• Headache or dizziness

• Numbness or tingling in the hands or feet

• Temporary flushing or warmth after injection

• Fatigue or drowsiness

Rare but serious risks include:

• Increased cortisol levels or hormonal imbalance

• Elevated insulin resistance or blood sugar levels

• Worsening of undiagnosed tumors (GH may promote growth in rare cases)

Always speak with your healthcare provider to weigh the benefits versus risks before starting Sermorelin.

What is Sermorelin Used For?

Sermorelin is used to stimulate the body’s natural production of growth hormone, which declines with age. It may be prescribed for:

• Age-related fatigue or low energy

• Poor sleep quality or disrupted sleep cycles

• Decreased muscle mass or strength

• Slowed metabolism or increased body fat

• Poor recovery from exercise or injury

• Cognitive fog or low mood

• Anti-aging or longevity optimization

Sermorelin does not replace growth hormone—it helps your body stimulate its own natural production.

Limitations of Use

Sermorelin is not a direct replacement for human growth hormone (HGH) and is not indicated for HGH deficiency due to pituitary failure or congenital disorders.

It should not be used for:

• Bodybuilding or athletic enhancement

• Children with open growth plates unless under pediatric endocrinology care

• Individuals with active cancer or unexplained masses

Who Should Not Use Sermorelin?

Avoid Sermorelin if you:

• Have a history of cancer, particularly pituitary, brain, or hormone-sensitive cancers

• Have untreated thyroid disease

• Are pregnant or breastfeeding

• Have active diabetic retinopathy

• Are allergic to Sermorelin or any of its ingredients

Inform your provider of any history of tumors, especially if they are hormone-related.

How to Take Sermorelin

Sermorelin is given via subcutaneous injection, usually in the abdomen or thigh, once daily—often in the evening to mimic natural growth hormone release during sleep.

General Instructions:

1. Wash hands thoroughly and clean the injection site with alcohol.

2. Draw the prescribed dose into a syringe.

3. Inject subcutaneously (just under the skin) using a fine needle.

4. Rotate injection sites to avoid irritation.

5. Dispose of the syringe safely.

Your provider will offer guidance on proper injection technique and storage.

What to Discuss with Your Provider

Before starting Sermorelin therapy, disclose if you:

• Have diabetes or insulin resistance

• Use thyroid medications or corticosteroids

• Have cardiovascular or renal disease

• Take hormone therapy or anabolic agents

• Have any history of cancer or tumors

Your provider may recommend baseline labs and periodic follow-ups.

Serious Side Effects

If you experience any of the following, stop therapy and seek medical care:

• Chest pain or irregular heartbeat

• Severe allergic reaction (swelling, rash, difficulty breathing)

• Signs of pituitary gland dysfunction

• Vision changes or severe headaches (may indicate increased intracranial pressure)

• Unusual mass or growth detection

Common Side Effects

These are typically mild and improve with time:

• Redness or swelling at the injection site

• Headache

• Drowsiness or lethargy

• Mild bloating or water retention

• Temporary tingling sensations

Monitor side effects and report anything unusual to your provider.

Monitoring During Sermorelin Therapy

Routine follow-up is essential to ensure the therapy is effective and safe. Your provider may monitor:

• IGF-1 levels (Insulin-like Growth Factor 1) to evaluate GH activity

• Fasting glucose or A1C to assess blood sugar response

• Thyroid function tests to rule out imbalances

• Sleep quality, energy levels, and recovery time as symptom indicators

Adjustments may be made to dose or frequency based on response.

Reporting Side Effects

To report serious side effects, contact your Good Medics provider or the FDA MedWatch program at 1-800-FDA-1088 or visit www.fda.gov/medwatch.

Note: This safety overview does not replace formal medical advice or the official product insert. Always follow your provider’s instructions and ask questions before starting any new therapy.